Digest: Egorov 2013 — Transcranial Laser + Magnetic Therapy in Glaucoma
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Clinical takeaway: In 165 glaucomatous eyes, combined transcranial low-intensity laser + magnetic therapy (vs magnetic alone) produced larger, more durable gains — expanded visual fields, reduced scotomas, stronger VEPs, and improved ocular blood flow.
Summary:
This study used infrared laser with a weak magnetic field transcranially. Patients showed measurable field enlargement, scotoma reduction, and improved conduction (VEP). Doppler confirmed better ocular blood flow.
Follow-up showed these gains were stable over time, suggesting real physiologic change. Though focused on glaucoma, the mechanisms — conduction and perfusion — are relevant in other optic-nerve compromise.
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Data & Methods
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Design & Population: 165 eyes with primary open-angle glaucoma (POAG), stages I–III.
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Intervention:
- Group 1: Combined transcranial magneto-laser therapy — low-intensity IR laser (wavelength ~0.89 μm, power <10 mW) + weak magnetic field (~30–50 mT), applied bitemporally over visual pathways.
- Group 2: Magnetic therapy only.
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Outcomes:
- Compared to magnetic therapy alone, the combined method led to:
- Visual fields: Average expansion +56% (range 38–74% by stage), with scotomas disappearing in 58% of cases (vs 22% with magnet alone).
- Electrophysiology: VEP amplitude rose 30–40%, latency shortened up to 15 ms.
- Ocular blood flow: Posterior ciliary artery velocity ↑ ~20%; resistance index ↓ ~20–25%.
- Compared to magnetic therapy alone, the combined method led to:
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Follow-up: Improvements remained stable at 3–6 months.
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